Humanitarian Data Exchange (HDX) is open platform for sharing data across crises and organisations.
Humanitarian Data Exchange API is a free Health API that requires no API key, is served over HTTPS and has unconfirmed CORS support.

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Yes. The Humanitarian Data Exchange API is listed in the Health category of the public-apis directory, which only includes APIs that are free or have a free tier. Check its documentation for rate limits and paid plans.
No. The Humanitarian Data Exchange API requires no authentication, so you can start making requests without signing up.
CORS support for the Humanitarian Data Exchange API is unknown. Test a request from the browser, and fall back to a server-side call if it is blocked.
Yes. The Humanitarian Data Exchange API is served over HTTPS, so it's safe to use in production.